LeHavreV1, France, Analysis, bibRecord, 000983

Tools for electrophysiology labs: a C coded dynamic-clamp on DSP board (aC/DC).

Identifieur interne : 000983 ( France/Analysis ); précédent : 000982; suivant : 000984

Tools for electrophysiology labs: a C coded dynamic-clamp on DSP board (aC/DC).

Auteurs : Sofiane Boussa [France] ; Jennifer Pasquier [France] ; Francois Leboulenger [France] ; Frank Le Foll [France] ; Alain Faure [France]

Source :

RBID : Hal:hal-00331615

English descriptors

mix :
- Cognitive Science, Data analysis, Neuron and plasticity, Synaptic plasticity.

Abstract

Dynamic-clamp represents an archetypal interdisciplinary approach in the field of computational neuroscience because it aims at establishing a dialog in real time between i) a numerical model and a spiking cell and ii) between neurobiologists and computer programmers. In this paper, we present a relative simple hardware solution for an efficient dynamic-clamp application. The prototype has been built around a DSP board (dsPIC 33F, Microchip INC). Our results demonstrate the high speed and flexibility of our setup with two examples using frog melanotrope cells as biological counterpart. First the fast inward sodium has been numerically-blocked in physiological recording solutions, and secondly, artificial autaptic GABAergic connections have been graft as recurrent neuroepithelial synapses on melanotrophs. Further experiments are in progress to examine the influences of the nature, amplitude and time-course of autaptic currents in cell spiking profile.

Url:

https://hal.archives-ouvertes.fr/hal-00331615

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Hal, to step Corpus: 000354
to stream Hal, to step Curation: 000354
to stream Hal, to step Checkpoint: 000573
to stream Main, to step Merge: 000D21
to stream Main, to step Curation: 000D07
to stream Main, to step Exploration: 000D07
to stream France, to step Extraction: 000983

Links to Exploration step

Hal:hal-00331615

Le document en format XML

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<front><div type="abstract" xml:lang="en">Dynamic-clamp represents an archetypal interdisciplinary approach in the field of computational neuroscience because it aims at establishing a dialog in real time between i) a numerical model and a spiking cell and ii) between neurobiologists and computer programmers. In this paper, we present a relative simple hardware solution for an efficient dynamic-clamp application. The prototype has been built around a DSP board (dsPIC 33F, Microchip INC). Our results demonstrate the high speed and flexibility of our setup with two examples using frog melanotrope cells as biological counterpart. First the fast inward sodium has been numerically-blocked in physiological recording solutions, and secondly, artificial autaptic GABAergic connections have been graft as recurrent neuroepithelial synapses on melanotrophs. Further experiments are in progress to examine the influences of the nature, amplitude and time-course of autaptic currents in cell spiking profile.</div>
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   |wiki=    Wicri/France
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   |texte=   Tools for electrophysiology labs: a C coded dynamic-clamp on DSP board (aC/DC).
}}

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Tools for electrophysiology labs: a C coded dynamic-clamp on DSP board (aC/DC).

Tools for electrophysiology labs: a C coded dynamic-clamp on DSP board (aC/DC).

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri